Best Investigation movies of 2000s

Actors : Karl Urban, Deobia Oparei, Dwayne Johnson, Rosamund Pike,
Directors : Andrzej Bartkowiak,

Space Marines are sent to investigate strange events at a research facility on Mars but find themselves at the mercy of genetically enhanced killing machines.

Actors : Tobey Maguire, Cate Blanchett, George Clooney, Beau Bridges,
Directors : Steven Soderbergh,

While in post-war Berlin to cover the Potsdam Conference, an American military journalist is drawn into a murder investigation which involves his former mistress and his driver.

Actors : Mila Kunis, Mark Wahlberg, Beau Bridges, Ludacris,
Directors : John Moore,

Coming together to solve a series of murders in New York City are a police detective whose family was slain as part of a conspiracy and an assassin out to avenge her sister's death. The duo will be hunted by the police, the mob, and a ruthless corporation.

Actors : Cory Fernandez, Juan Carlos Hernández, Tracy Morgan, Bruce Willis,
Directors : Kevin Smith,

Jimmy's rare baseball card is robbed. Since it's his only hope to pay for his daughter's upcoming wedding, he recruits his cop partner Paul to track down the robber, a memorabilia-obsessed gangster.

Actors : Elias Koteas, Francesca Neri, John Leguizamo, Arnold Schwarzenegger,
Directors : Andrew Davis,

After his family is killed by a terrorist act, a firefighter goes in search of the one responsible.

Actors : Samuel L. Jackson, Tim Daly, Connie Nielsen, John Travolta,
Directors : John McTiernan,

A DEA agent investigates the disappearance of a legendary Army ranger drill sergeant and several of his cadets during a training exercise gone severely awry.

Actors : Jennifer Jason Leigh, Michael Nuccio, Mark Ruffalo, Meg Ryan,
Directors : Jane Campion,

New York City writing professor, Frannie Avery, has an affair with a police detective, who is investigating the murder of a beautiful young woman in her neighborhood.

Actors : Samantha Morton, Tim Robbins, Togo Igawa, Om Puri,
Directors : Michael Winterbottom,

A futuristic Brief Encounter (1945), this is a love story in which the romance is doomed by genetic incompatibility.

Actors : Tate Donovan, Craig Gellis, Max Thieriot, Emma Roberts,
Directors : Andrew Fleming,

Teen detective Nancy Drew accompanies her father on a business trip to Los Angeles, where she happens upon clues to a murder mystery involving a movie star.

Actors : Gary Sinise, Don Cheadle, Connie Nielsen, Tim Robbins,
Directors : Brian De Palma,

When the first manned mission to Mars meets with a catastrophic and mysterious disaster after reporting an unidentified structure, a rescue mission is launched to investigate the tragedy and bring back any survivors.

Actors : Kate Beahan, Ellen Burstyn, Leelee Sobieski, Nicolas Cage,
Directors : Neil LaBute,

A sheriff investigating the disappearance of a young girl from a small island discovers there's a larger mystery to solve among the island's secretive, neo-pagan community.

Actors : Hilary Swank, David Morrissey, Idris Elba, AnnaSophia Robb,
Directors : Stephen Hopkins,

A former Christian missionary, who specializes in debunking religious phenomena, investigates a small town which seems to be suffering from the 10 biblical plagues.

Actors : Elias Koteas, Milla Jovovich, Will Patton, Hakeem Kae-Kazim,
Directors : Olatunde Osunsanmi,

A thriller involving an ongoing unsolved mystery in Alaska, where one town has seen an extraordinary number of unexplained disappearances during the past 40 years and there are accusations of a federal cover up.

Actors : Jean Reno, Andy Garcia, Steve Martin, Emily Mortimer,
Directors : Harald Zwart,

Insp. Jacques Clouseau teams up with a squad of International detectives who are just as bumbling as he is. Their mission: Stop a globe-trotting thief who specializes in stealing historical artifacts.

Actors : Alden Ehrenreich, Vincent Gallo, Silvia Pérez, Maribel Verdú,
Directors : Francis Ford Coppola,

Bennie travels to Buenos Aires to find his long-missing older brother, a once-promising writer who is now a remnant of his former self. Bennie's discovery of his brother's near-finished play might hold the answer to understanding their shared past and renewing their bond.

Actors : Edward Burns, Kelsey Grammer, Robert De Niro, Avery Brooks,
Directors : John Herzfeld,

A homicide detective and a fire marshal must stop a pair of murderers who commit videotaped crimes to become media darlings.

Actors : Aaron Eckhart, Jeremy Northam, Jennifer Ehle, Gwyneth Paltrow,
Directors : Neil LaBute,

A pair of literary sleuths unearth the amorous secret of two Victorian poets only to find themselves falling under a passionate spell.

Actors : Eion Bailey, LL Cool J, Val Kilmer, Christian Slater,
Directors : Renny Harlin,

Trainees in the FBI's psychological profiling program must put their training into practice when they discover a killer in their midst.

Actors : Michael Keaton, Deborah Kara Unger, Chandra West, Ian McNeice,
Directors : Geoffrey Sax,

An architect's desire to speak with his wife from beyond the grave, becomes an obsession with supernatural repercussions.

Actors : Tom Sizemore, Benjamin Bratt, Carrie-Anne Moss, Val Kilmer,
Directors : Antony Hoffman,

Astronauts, and their robotic dog AMEE (Autonomous Mapping Evaluation and Evasion), search for solutions to save a dying Earth by searching on Mars, only to have the mission go terribly awry.