Best Female Lead movies of 2000s

Actors : Anna Chancellor, Andie MacDowell, Kenny Doughty, Imelda Staunton,
Directors : John McKay,

Three female friends behave badly.

Actors : Will Patton, Nicole Beharie, Alfre Woodard, Tim Blake Nelson,
Directors : Tim Disney,

A single mother struggles to clear her name after being wrongly accused and arrested for dealing drugs in an impoverished town in Texas.

Actors : Merab Ninidze, Juliane Köhler, Matthias Habich, Sidede Onyulo,
Directors : Caroline Link,

A German Jewish refugee family moves to and adjusts to a farm life in 1930s Kenya.

Actors : Scott Porter, Alexis Bledel, Anna Chlumsky, Bryan Greenberg,
Directors : Julio DePietro,

Ambitious young Manhattanite and urban conservationist Beth wants it all: a good job, good friends, and a good guy to share the city with. Of course that last one is often the trickiest of ...

Actors : Mira Sorvino, Ben Kingsley, Rachael Stirling, Jay Rodan,
Directors : Clare Peploe,

A princess is determined to restore her homeland's throne to its rightful heir, a young prince with whom she falls in love.

Actors : Julianne Moore, Mark Ruffalo, Yûsuke Iseya, Gael García Bernal,
Directors : Fernando Meirelles,

A city is ravaged by an epidemic of instant white blindness.

Actors : Noah Emmerich, Ann Magnuson, Jon Favreau, Famke Janssen,
Directors : Valerie Breiman,

When her rather explicit copy is rejected, magazine journalist Kate is asked by her editor to come up with an article on loving relationships instead, and to do so by the end of the day. ...

Actors : Morjana Alaoui, Catherine Bégin, Robert Toupin, Mylène Jampanoï,
Directors : Pascal Laugier,

A young woman's quest for revenge against the people who kidnapped and tormented her as a child leads her and a friend, who is also a victim of child abuse, on a terrifying journey into a living hell of depravity.

Actors : Anna Paquin, Patrick Stewart, Alfred Molina, Anne Suzuki,
Directors : Katsuhiro Ôtomo,

In 1860s Britain, a boy inventor finds himself caught in the middle of a deadly conflict over a revolutionary advance in steam power.

Actors : Shabnam Toloui, Arita Shahrzad, Pegah Ferydoni, Orsolya Tóth,

Against the tumultuous backdrop of Iran's 1953 CIA-backed coup d'état, the destinies of four women converge in a beautiful orchard garden, where they find independence, solace and companionship.

Actors : Joanna Moukarzel, Gisèle Aouad, Yasmine Al Massri, Nadine Labaki,
Directors : Nadine Labaki,

A romantic comedy centered on the daily lives of five Lebanese women living in Beirut.

Actors : Anaïs Reboux, Roxane Mesquida, Libero De Rienzo, Arsinée Khanjian,
Directors : Catherine Breillat,

Two sisters confront their sexual attitudes and experiences while on a family holiday.

Actors : Chris Messina, David Margulies, Jennifer Westfeldt, Jason Alexander,
Directors : Robert Cary,

A hastily married couple quickly devolve into a life of affairs, meddling parents, and therapy.

Actors : Damian Jewan Lee, Donald Holden, Curtis Cotton III, Candace Evanofski,
Directors : David Gordon Green,

A group of children, in a depressed small town, band together to cover up a tragic mistake one summer.

Actors : Freddy Rodríguez, Josh Brolin, Marley Shelton, Rose McGowan,
Directors : Robert Rodriguez,

After an experimental bio-weapon is released, turning thousands into zombie-like creatures, it's up to a rag-tag group of survivors to stop the infected and those behind its release.

Actors : Frances McDormand, Marton Csokas, Sophie Okonedo, Charlize Theron,
Directors : Karyn Kusama,

Aeon Flux is a mysterious assassin working for the Monicans, a group of rebels trying to overthrow the government. When she is sent on a mission to kill the Chairman, a whole new mystery is found.

Actors : Frederick Weller, Neve Campbell, Dominic Chianese, Ashley Shelton,
Directors : James Toback,

Feeling undervalued by her boyfriend, a young woman begins to explore her sexuality with other people.

Actors : Misaki Itô, Misa Uehara, Yui Ichikawa, Megumi Okina,
Directors : Takashi Shimizu,

A mysterious and vengeful spirit marks and pursues anybody who dares enter the house in which it resides.

Actors : Maïwenn, Philippe Nahon, Franck Khalfoun, Cécile De France,
Directors : Alexandre Aja,

Best friends Marie and Alexia decide to spend a quiet weekend at Alexia's parents' secluded farmhouse. But on the night of their arrival, the girls' idyllic getaway turns into an endless night of horror.

Actors : Asma Al Shiukhy, Hiam Abbass, Freida Pinto, Willem Dafoe,
Directors : Julian Schnabel,

A drama centered on an orphaned Palestinian girl growing up in the wake of Arab-Israeli war who finds herself drawn into the conflict.