Best Female Lead movies of 2000s

Actors : Arielle Kebbel, Edison Chen, Amber Tamblyn, Sarah Michelle Gellar,
Directors : Takashi Shimizu,

Three interwoven stories about a terrible curse. A young woman encounters a malevolent supernatural force while searching for her missing sister in Tokyo; a mean high school prank goes horribly wrong; a woman with a deadly secret moves into a Chicago apartment building.

Actors : John Howard, Stelios Yiakmis, Gabriel Byrne, Laura Linney,
Directors : Ray Lawrence,

Stewart Kane, an Irishman living in the Australian town of Jindabyne, is on a fishing trip in isolated hill country with three other men when they discover the body of a murdered girl in ...

Actors : Alexis Georgoulis, Nia Vardalos, Richard Dreyfuss, Rachel Dratch,
Directors : Donald Petrie,

A travel guide rediscovers her romantic side on a trip around Greece.

Actors : Fatoumata Coulibaly, Maimouna Hélène Diarra, Salimata Traoré, Dominique Zeïda,
Directors : Ousmane Sembene,

When a woman shelters a group of girls from suffering female genital mutilation, she starts a conflict that tears her village apart.

Actors : Katie Cassidy, Tessa Thompson, Camilla Belle, Tommy Flanagan,
Directors : Simon West,

During a babysitting gig, a high-school student is harassed by an increasingly threatening prank caller.

Actors : Lynette Curran, Damian de Montemas, Abbie Cornish, Sam Worthington,
Directors : Cate Shortland,

A young girl flees her hometown and arrives in the Australian Alps, where new experiences help her learn the differences between sex and love.

Actors : Rosario Flores, Leonor Watling, Javier Cámara, Darío Grandinetti,
Directors : Pedro Almodóvar,

Two men share an odd friendship while they care for two women who are both in deep comas.

Actors : Adam Brody, John Krasinski, Anna Faris, Roscoe Lee Browne,
Directors : Gregg Araki,

After a young actress unknowingly eats her roommate's marijuana cupcakes, her day becomes a series of misadventures.

Actors : Charlyne Yi, Jake Johnson, Gill Summers, Michael Cera,
Directors : Nicholas Jasenovec,

Charlyne Yi embarks on a quest across America to make a documentary about the one subject she doesn't fully understand: Love.

Actors : Wes Bentley, Rachel Nichols, Simon Reynolds, Philip Akin,
Directors : Franck Khalfoun,

A businesswoman is pursued by a psychopath after being locked in a parking garage on Christmas Eve.

Actors : Ian McShane, Renée Zellweger, Bradley Cooper, Jodelle Ferland,
Directors : Christian Alvart,

A social worker fights to save a girl from her abusive parents, only to discover that the situation is more dangerous than she ever expected.

Actors : Tom Wilkinson, Milena Vukotic, Helen Hunt, Scarlett Johansson,
Directors : Mike Barker,

While retaining her secret identity, the illustrious Mrs. Erlynne (Hunt) saves Lady Windemere (Johansson) from making a grand social faux-pas with the scoundrelly Lord Darlington (Moore).

Actors : Jason Biggs, Lake Bell, Paul Rudd, Eva Longoria,
Directors : Jeff Lowell,

A ghost tries to sabotage her former boyfriend's current relationship with a psychic.

Actors : Chiara Mastroianni, Ludivine Sagnier, Clotilde Hesme, Louis Garrel,
Directors : Christophe Honoré,

A musical interpretation of three lovers living in Paris.

Actors : Brittany Murphy, Ron Livingston, Kathy Bates, Holly Hunter,
Directors : Nick Hurran,

A woman snoops through her boyfriend's palm pilot and reveals his former girlfriends, which causes her to question why they're still listed in his little black book.

Actors : Michèle Caucheteux, Jean-Claude Donda, Michel Robin, Monica Viegas,
Directors : Sylvain Chomet,

When her grandson is kidnapped during the Tour de France, Madame Souza and her beloved pooch Bruno team up with the Belleville Sisters--an aged song-and-dance team from the days of Fred Astaire--to rescue him.

Actors : Chieko Baishô, Takuya Kimura, Tatsuya Gashûin, Akihiro Miwa,
Directors : Hayao Miyazaki,

When an unconfident young woman is cursed with an old body by a spiteful witch, her only chance of breaking the spell lies with a self-indulgent yet insecure young wizard and his companions in his legged, walking castle.

Actors : Daniel Franzese, Andrew Howard, Sarah Butler, Jeff Branson,
Directors : Steven R. Monroe,

A writer who is brutalized during her cabin retreat seeks revenge on her attackers, who left her for dead.

Actors : Abigail Breslin, Julia Ormond, Stanley Tucci, Joan Cusack,
Directors : Patricia Rozema,

Set in Cincinnati at the height of the Great Depression, Kit Kittredge, a resourceful young girl, helps her mother run a boardinghouse after her father loses his job.

Actors : Robert Englund, Jenna Jameson, Roxy Saint, Penny Vital,
Directors : Jay Lee,

A zombie epidemic spreads throughout a strip club in Nebraska.