Best Female Lead movies of 2000s

Actors : Olivia Bonamy, Michaël Cohen, Adriana Mocca, Maria Roman,

Lucas and Clementine live peacefully in their isolated country house, but one night they wake up to strange noise... they're not alone... and a group of hooded assailants begin to terrorize them throughout the night.

Actors : Kirsten Dunst, Eddie Izzard, Edward Herrmann, Cary Elwes,
Directors : Peter Bogdanovich,

Semi-true story of the Hollywood murder that occurred at a star-studded gathering aboard William Randolph Hearst's yacht in 1924.

Actors : Samaire Armstrong, Lindsay Lohan, Bree Turner, Chris Pine,
Directors : Donald Petrie,

Manhattanite Ashley is known to many as the luckiest woman around. After a chance encounter with a down-and-out young man, however, she realizes that she's swapped her fortune for his.

Actors : Elisabeth Helander, Jörgen Nohall, Jan Wikbladh, Björn Englund,
Directors : Roy Andersson,

You, the Living is a film about humankind, its greatness and its baseness, joy and sorrow, its self-confidence and anxiety, its desire to love and be loved.

Actors : Tara Strong, Elizabeth Daily, Cathy Cavadini, Roger Jackson,
Directors : Craig McCracken,

The movie shows the origin of the Powerpuff Girls before the cartoon series. It explains why they were born and why they dedicated their lives to fighting crime and the forces of evil.

Actors : Samuel L. Jackson, Julianne Moore, Edie Falco, Ron Eldard,
Directors : Joe Roth,

A black police detective must solve a strange case of a kidnapped boy and deal with a big racial protest.

Actors : Jean-Pierre Bacri, Agnès Jaoui, Marilou Berry, Laurent Grévill,
Directors : Agnès Jaoui,

A french girl gifted with a great voice, has a complex about her weight and her appearance.

Actors : Jeremy Sisto, Jennifer Lopez, Jim Caviezel, Terrence Howard,
Directors : Luis Mandoki,

A mysterious man is drawn to a feisty female police officer and a unusual relationship ensues, as not everything is as it seems.

Actors : Rachel Hurd-Wood, Caitlin Stasey, Deniz Akdeniz, Lincoln Lewis,
Directors : Stuart Beattie,

When their country is invaded and their families are taken, eight unlikely high school teenagers band together to fight.

Actors : Jeremy Sisto, Desmond Harrington, Eliza Dushku, Emmanuelle Chriqui,
Directors : Rob Schmidt,

Six people find themselves trapped in the woods of West Virginia, hunted down by "cannibalistic mountain men grossly disfigured through generations of in-breeding."

Actors : Isaiah Stone, Jennifer Lawrence, Garret Dillahunt, John Hawkes,
Directors : Debra Granik,

An unflinching Ozark Mountain girl hacks through dangerous social terrain as she hunts down her drug-dealing father while trying to keep her family intact.

Actors : Dakota Fanning, Brittany Murphy, Heather Locklear, Jesse Spencer,
Directors : Boaz Yakin,

A grown-up woman, who kept her childish instincts and behavior, starts working as a nanny of a 8-year-old girl, who actually acts like an adult. But in the end everything turns to its right places.

Actors : Mariana Loyola, Claudia Celedón, Catalina Saavedra, Andrea García-Huidobro,
Directors : Sebastián Silva,

A drama centered on a maid trying to hold on to her position after having served a family for 23 years.

Actors : Leo Fitzpatrick, Robert Wisdom, Maria Thayer, Selma Blair,
Directors : Todd Solondz,

College and high school serve as the backdrop for two stories about dysfunction and personal turmoil.

Actors : Matthew Broderick, Helen Hunt, Bette Midler, Colin Firth,
Directors : Helen Hunt,

39-year-old April Epner's childish husband and school teacher colleague Benjamin/Ben leaves her, but with her biological clock ticking ever more loudly. Her dying bossy adoptive mother is ...

Actors : Mozhan Marnò, Navid Negahban, Shohreh Aghdashloo, Jim Caviezel,
Directors : Cyrus Nowrasteh,

A distressed woman, desperately asks for a meeting with a journalist, to disclose the cruel and inhumane punishment of her niece.

Actors : Kristen Bell, Anjelica Huston, Josh Duhamel, Danny DeVito,
Directors : Mark Steven Johnson,

Beth is a young, ambitious New Yorker who is completely unlucky in love. However, on a whirlwind trip to Rome, she impulsively steals some coins from a reputed fountain of love, and is then aggressively pursued by a band of suitors.

Actors : Jordana Brewster, Matt Bomer, Diora Baird, Taylor Handley,
Directors : Jonathan Liebesman,

Before being sent to serve in Vietnam, two brothers and their girlfriends take one last road trip, but when they get into an accident, a terrifying experience will take them to a secluded house of horrors, with a chainsaw-wielding killer.

Actors : Ebru Ceylan, Nuri Bilge Ceylan, Mehmet Eryilmaz, Nazan Kesal,
Directors : Nuri Bilge Ceylan,

A dowdy university instructor Isa is an inattentive husband to his younger, TV-business wife Bahar. Self-absorbed and selfish, Isa only communicates in the most rudimentary way, while she, similarly, detaches into crying jags and juvenile behavior.

Actors : Siobhan Fallon Hogan, J.K. Simmons, Renée Zellweger, Harry Connick Jr.,
Directors : Jonas Elmer,

A Miami businesswoman adjusts to her new life in a tiny Minnesota town.