Inspired by true incidents, "Runway 34" revolves around Captain Vikrant Khanna played by Ajay Devgn, a flying prodigy, whose flight takes a mysterious course after take-off from an international destination.
Shivaay is a Himalayan mountaineer who is an innocent and yet is capable of transforming into a mean destroyer when he needs to protect his family.
Ajay's life turns upside down when he learns that his wife Piya has Alzheimer and he has no option, but to leave his wife in a mental hospital.