When their new next-door neighbors turn out to be a sorority even more debaucherous than the fraternity previously living there, Mac and Kelly team with their former enemy, Teddy, to bring the girls down.
Following Kick-Ass' heroics, other citizens are inspired to become masked crusaders. But Red Mist leads his own group of evil supervillains to get revenge, kill Kick-Ass and destroy everything he stands for.