Best Adult Comedy movies of 2000s

Actors : Anne Hathaway, Jake Gyllenhaal, Oliver Platt, Judy Greer,
Directors : Edward Zwick,

A young woman suffering from Parkinson's befriends a drug rep working for Pfizer in 1990s Pittsburgh.

Actors : Felicity Huffman, Andrea James, Fionnula Flanagan, Kevin Zegers,
Directors : Duncan Tucker,

A preoperative transgender woman takes an unexpected journey when she learns that she fathered a son, now a teenage runaway hustling on the streets of New York.

Actors : Cameron Diaz, Bill Murray, Drew Barrymore, Lucy Liu,
Directors : McG,

Three women, detectives with a mysterious boss, retrieve stolen voice-ID software, using martial arts, tech skills, and sex appeal.

Actors : Macaulay Culkin, Patrick Fugit, Jena Malone, Mandy Moore,
Directors : Brian Dannelly,

When a girl attending a Christian high school becomes pregnant, she finds herself ostracized and demonized, as all of her former friends turn on her.

Actors : Josh Hartnett, Paulo Costanzo, Adam Trese, Shannyn Sossamon,
Directors : Michael Lehmann,

After a brutal break-up, a young man vows to stay celibate during the forty days of Lent, but finds the girl of his dreams and is unable to do anything about it.

Actors : Campbell Scott, Isabella Rossellini, Jesse Eisenberg, Elizabeth Berkley,
Directors : Dylan Kidd,

After breaking up with his lover and boss, a smooth-talking man takes his teenaged nephew out on the town in search of sex.

Actors : Renée Zellweger, Ewan McGregor, David Hyde Pierce, Sarah Paulson,
Directors : Peyton Reed,

In 1962 New York City, love blossoms between a playboy journalist and a feminist advice author.

Actors : Renée Zellweger, Anthony Anderson, Mongo Brownlee, Jim Carrey,

A nice-guy cop with dissociative identity disorder must protect a woman on the run from a corrupt ex-boyfriend and his associates.

Actors : Jason Biggs, Shannon Elizabeth, Seann William Scott, Alyson Hannigan,
Directors : J.B. Rogers,

In this sequel to the hit comedy American Pie (1999), the high school students are now in college. These close friends decide to meet up at the beach house for some fun.

Actors : Scott Mechlowicz, Jacob Pitts, Michelle Trachtenberg, Travis Wester,

Dumped by his girlfriend, a high school grad decides to embark on an overseas adventure in Europe with his friends.

Actors : Blake Lively, Adam Herschman, Justin Long, Jonah Hill,
Directors : Steve Pink,

A high school slacker who's rejected by every school he applies to opts to create his own institution of higher learning, the South Harmon Institute of Technology, on a rundown piece of property near his hometown.

Actors : Jessica Biel, Ian Somerhalder, James Van Der Beek, Shannyn Sossamon,
Directors : Roger Avary,

The incredibly spoiled and overprivileged students of Camden College are a backdrop for an unusual love triangle between a drug dealer, a virgin and a bisexual classmate.

Actors : Jessica Biel, Dan Aykroyd, Kevin James, Adam Sandler,
Directors : Dennis Dugan,

Two straight, single Brooklyn firefighters pretend to be a gay couple in order to receive domestic partner benefits.

Actors : Clark Duke, Amanda Crew, Josh Zuckerman, James Marsden,
Directors : Sean Anders,

A high school senior drives cross-country with his best friends to hook up with a babe he met online.

Actors : Craig Bierko, Bill Pullman, Anna Faris, Regina Hall,
Directors : David Zucker,

Cindy finds out the house she lives in is haunted by a little boy and goes on a quest to find out who killed him and why. Also, Alien "Tr-iPods" are invading the world and she has to uncover the secret in order to stop them.

Actors : Giuseppe Sulfaro, Matilde Piana, Luciano Federico, Monica Bellucci,
Directors : Giuseppe Tornatore,

Amidst the war climate, a teenage boy discovering himself becomes love-stricken by Malèna, a sensual woman living in a small, narrow-minded Italian town.

Actors : Anjelica Huston, Sam Rockwell, Kathryn Alexander, Kelly Macdonald,
Directors : Clark Gregg,

A sex-addicted con-man pays for his mother's hospital bills by playing on the sympathies of those who rescue him from choking to death.

Actors : Katherine Heigl, Bree Turner, Eric Winter, Gerard Butler,
Directors : Robert Luketic,

A romantically challenged morning show producer is reluctantly embroiled in a series of outrageous tests by her chauvinistic correspondent to prove his theories on relationships and help ...

Actors : Andrea Riseborough, Bob Hoskins, Jaime Winstone, Sally Hawkins,
Directors : Nigel Cole,

A dramatization of the 1968 strike at the Ford Dagenham car plant, where female workers walked out in protest against sexual discrimination.

Actors : Matthew Goode, Piper Perabo, Lena Headey, Celia Imrie,
Directors : Ol Parker,

A newlywed bride becomes infatuated with another woman, who questions her sexual orientation, promoting a stir among the bride's family and friends.