Jim, Michelle, Stifler, and their friends reunite in East Great Falls, Michigan for their high school reunion.
It's the wedding of Jim and Michelle and the gathering of their families and friends, including Jim's old friends from high school and Michelle's little sister.
In this sequel to the hit comedy American Pie (1999), the high school students are now in college. These close friends decide to meet up at the beach house for some fun.
Manny, Sid, and Diego discover that the ice age is coming to an end, and join everybody for a journey to higher ground. On the trip, they discover that Manny, in fact, is not the last of the woolly mammoths.