After splitting with the Joker, Harley Quinn joins superheroes Black Canary, Huntress and Renee Montoya to save a young girl from an evil crime lord.
In the near future, convicts are offered the chance to volunteer as medical subjects to shorten their sentence. One such subject for a new drug capable of generating feelings of love begins questioning the reality of his emotions.
A storm rages. A young girl is kidnapped. Her mother teams up with the mysterious woman next door to pursue the kidnapper, a journey that tests their limits and exposes shocking secrets from their pasts.