In the haunted corridors of the Lockhouse asylum, a psychotic doctor conducts gruesome experiments on his patients. 70 years later the asylum opens as a bed and breakfast, and the door to hell is opened along with it.
A Dominatrix is brutally murdered by thugs. Returning from the grave as Zombinatrix, she takes great pleasure in incorporating her sadistic S&M kinks into killing anyone crossing her path. After all, she is into whips and BRAINS.