Lonely guy Fred Stoller is thrilled when his good buddy, Vinnie D'Angelo, the world's happiest agoraphobic and fattest vegetarian, comes to live with him, until Vinnie also proves to be the world's most maddening roommate.
Tormented by the memories of her late-husband's suicide, Vanessa's life is further complicated by the arrival of her step-son, who will soon inherit all of his father's wealth.