The missing case of a teacher named Prakashan is reported at the police station where John Luther works as a CI. As the investigation progresses, John meets with an accident in a scuffle while investigating another case.
Rohini Pranab, a cardiac surgeon and a social worker, sets out to find the girls kidnapped from her NGO. She is joined by Naveen, who is looking for his kidnapped sister. The duo goes deeper into the human trafficking mafia in Karnataka.
An array of ex-college mates are being murdered by a common friend, Zachariah Pothen. Meanwhile, the police tries to stop the murders and a journalist tries to uncover the truth.
Two months have passed since three youngsters belonging to a political outfit have gone missing. C.I Srikanth aided by C.P Aby Mathew are given a final two days to solve the mystery.